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ONTOLOGY REPORT - ANNOTATIONS

Term:receptor tyrosine kinase binding
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Accession:GO:0030971 term browser browse the term
Definition:Binding to a receptor that possesses protein tyrosine kinase activity.
Synonyms:related_synonym: transmembrane receptor protein tyrosine kinase ligand binding

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receptor tyrosine kinase binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP4 acid phosphatase 4 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:43,838,103...43,843,715
Ensembl chr 6:43,838,321...43,843,654 		JBrowse link
G ALKAL1 ALK and LTK ligand 1 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 8:48,641,163...48,672,392
Ensembl chr 8:48,645,771...48,669,954 		JBrowse link
G ALKAL2 ALK and LTK ligand 2 enables IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr14:107,438,932...107,448,066
Ensembl chr14:107,439,646...107,444,580 		JBrowse link
G ANGPT1 angiopoietin 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 8:102,020,346...102,268,443 JBrowse link
G ANGPT2 angiopoietin 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:6,283,619...6,345,320
Ensembl chr 8:6,280,584...6,344,729 		JBrowse link
G ANGPT4 angiopoietin 4 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:55,619,463...55,654,843
Ensembl chr 2:55,620,694...55,654,001 		JBrowse link
G ANXA5 annexin A5 ISO intracellular domain of Kdr RGD PMID:10329451 RGD:2292112 NCBI chr 7:68,940,365...68,970,324
Ensembl chr 7:68,940,304...68,970,811 		JBrowse link
G ARHGEF16 Rho guanine nucleotide exchange factor 16 enables ISO (PMID:20679435) UniProt PMID:20679435 NCBI chr20:128,204,517...128,229,866 JBrowse link
G ARTN artemin enables IEA InterPro GO_REF:0000002 NCBI chr20:88,869,463...88,874,036
Ensembl chr20:88,869,941...88,871,049 		JBrowse link
G CADM4 cell adhesion molecule 4 enables ISO (MGI:6270911|PMID:23611113) UniProt PMID:23611113 MGI:6270911 NCBI chr 6:37,143,477...37,161,524
Ensembl chr 6:37,140,676...37,161,524 		JBrowse link
G CBL Cbl proto-oncogene enables IEA TreeGrafter GO_REF:0000118 NCBI chr 1:110,581,049...110,679,284
Ensembl chr 1:110,581,143...110,674,481 		JBrowse link
G CBLB Cbl proto-oncogene B enables IEA TreeGrafter GO_REF:0000118 NCBI chr22:74,961,831...75,181,307
Ensembl chr22:74,961,859...75,178,548 		JBrowse link
G CBLC Cbl proto-oncogene C enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:38,257,418...38,285,534
Ensembl chr 6:38,257,672...38,280,051 		JBrowse link
G CD2 CD2 molecule ISO RGD PMID:18178839 RGD:2316555 NCBI chr20:16,954,925...16,970,066
Ensembl chr20:16,953,811...16,970,044 		JBrowse link
G CPNE3 copine 3 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:81,697,014...81,744,851
Ensembl chr 8:81,711,571...81,745,019 		JBrowse link
G CRK CRK proto-oncogene, adaptor protein enables IEA TreeGrafter GO_REF:0000118 NCBI chr16:1,102,485...1,135,225
Ensembl chr16:1,102,348...1,135,166 		JBrowse link
G DAZAP2 DAZ associated protein 2 enables IEA Ensembl GO_REF:0000107 NCBI chr11:47,437,957...47,443,042
Ensembl chr11:47,437,746...47,443,243 		JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 enables ISO (MGI:3835221|PMID:19038220) UniProt PMID:19038220 MGI:3835221 NCBI chr 5:4,109,612...4,139,789 JBrowse link
G DOCK4 dedicator of cytokinesis 4 enables IEA Ensembl GO_REF:0000107 NCBI chr21:80,548,079...81,022,410
Ensembl chr21:80,547,655...80,812,702 		JBrowse link
G DUSP3 dual specificity phosphatase 3 enables IEA Ensembl GO_REF:0000107 NCBI chr16:62,622,667...62,637,129
Ensembl chr16:62,622,663...62,637,127 		JBrowse link
G EIF3A eukaryotic translation initiation factor 3 subunit A ISO RGD PMID:10691301 RGD:10003117 NCBI chr 9:111,828,858...111,887,546
Ensembl chr 9:111,830,988...111,887,518 		JBrowse link
G ELMO2 engulfment and cell motility 2 enables ISO (PMID:20679435) UniProt PMID:20679435 NCBI chr 2:17,477,425...17,518,814
Ensembl chr 2:17,489,658...17,518,843 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 enables ISO (PMID:7556068) BHF-UCL PMID:7556068 NCBI chr16:66,435,488...66,464,993
Ensembl chr16:66,434,251...66,464,952 		JBrowse link
G FIZ1 FLT3 interacting zinc finger 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:48,179,681...48,187,568
Ensembl chr 6:48,179,524...48,185,879 		JBrowse link
G FLT3LG fms related receptor tyrosine kinase 3 ligand enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:42,653,820...42,665,017
Ensembl chr 6:42,654,412...42,660,458 		JBrowse link
G FNTA farnesyltransferase, CAAX box, subunit alpha enables IEA Ensembl GO_REF:0000107 NCBI chr 8:41,057,798...41,088,210
Ensembl chr 8:41,057,603...41,087,705 		JBrowse link
G GAS6 growth arrest specific 6 enables IEA Ensembl GO_REF:0000107 Ensembl chr 3:91,720,882...91,738,069 JBrowse link
G GDNF glial cell derived neurotrophic factor enables IEA InterPro GO_REF:0000002 NCBI chr 4:36,662,033...36,691,761
Ensembl chr 4:36,665,009...36,684,257 		JBrowse link
G GFRAL GDNF family receptor alpha like enables IEA Ensembl GO_REF:0000107 NCBI chr17:16,154,054...16,221,616
Ensembl chr17:16,155,423...16,216,101 		JBrowse link
G GRB14 growth factor receptor bound protein 14 enables IEA Ensembl GO_REF:0000107 NCBI chr10:49,952,835...50,085,274
Ensembl chr10:49,953,059...50,084,869 		JBrowse link
G HYAL2 hyaluronidase 2 enables ISO (PMID:12676986) UniProt PMID:12676986 NCBI chr22:11,704,422...11,710,013
Ensembl chr22:11,703,790...11,709,454 		JBrowse link
G ITGAX integrin subunit alpha X enables IEA Ensembl GO_REF:0000107 NCBI chr 5:28,058,172...28,087,253
Ensembl chr 5:28,058,456...28,086,838 		JBrowse link
G LOC103214855 growth arrest-specific protein 6 enables ISO (PMID:7634325) UniProt PMID:7634325 NCBI chr 3:91,720,871...91,762,712 JBrowse link
G LOC103222955 uncharacterized LOC103222955 enables IEA TreeGrafter GO_REF:0000118 NCBI chr19:4,855,633...4,889,674
Ensembl chr19:4,855,611...4,890,302 		JBrowse link
G LOC103233559 SHC-transforming protein 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:151,955...193,626 JBrowse link
G LRP4 LDL receptor related protein 4 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:18,393,489...18,474,514
Ensembl chr 1:18,413,513...18,471,444 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 enables ISO (MGI:6148351|PMID:18762249)
(PMID:18762249)		 WB PMID:18762249 MGI:6148351 NCBI chr13:15,284,927...15,360,539
Ensembl chr13:15,284,923...15,360,832 		JBrowse link
G MST1 macrophage stimulating 1 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr22:11,078,662...11,083,885
Ensembl chr22:11,074,114...11,083,368 		JBrowse link
G MYOC myocilin enables ISO (MGI:5527213|PMID:23897819) UniProt PMID:23897819 MGI:5527213 NCBI chr25:57,458,615...57,475,329
Ensembl chr25:57,459,374...57,475,322 		JBrowse link
G NCK1 NCK adaptor protein 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr15:53,501,152...53,595,500
Ensembl chr15:53,500,623...53,523,576 		JBrowse link
G NCK2 NCK adaptor protein 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr14:9,412,677...9,515,565
Ensembl chr14:9,437,301...9,515,561 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO RGD PMID:18261979 RGD:2302206 NCBI chr23:45,904,926...46,031,804
Ensembl chr23:45,904,873...46,031,125 		JBrowse link
G NRG1 neuregulin 1 enables ISO PMID:22659029 MGI PMID:22659029 RGD:11035334 NCBI chr 8:29,745,984...30,862,140
Ensembl chr 8:30,635,803...30,856,487 		JBrowse link
G NRTN neurturin enables IEA InterPro GO_REF:0000002 NCBI chr 6:5,444,514...5,458,769
Ensembl chr 6:5,444,878...5,458,617 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO RGD PMID:16801538 RGD:10043330 NCBI chr12:95,477,612...95,836,734
Ensembl chr12:95,479,447...95,620,364 		JBrowse link
G PCNA proliferating cell nuclear antigen enables IEA Ensembl GO_REF:0000107 NCBI chr 2:32,936,600...32,953,635
Ensembl chr 2:32,948,196...32,953,991 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:18292389 RGD:4108493 NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519 		JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:16,620,673...16,637,511
Ensembl chr 6:16,621,606...16,636,937 		JBrowse link
G PITPNM1 phosphatidylinositol transfer protein membrane associated 1 enables ISO (PMID:10022914) UniProt PMID:10022914 NCBI chr 1:6,760,208...6,774,006
Ensembl chr 1:6,761,369...6,775,983 		JBrowse link
G PITPNM2 phosphatidylinositol transfer protein membrane associated 2 enables ISO (PMID:10022914) UniProt PMID:10022914 NCBI chr11:118,323,798...118,493,994
Ensembl chr11:118,324,978...118,375,696 		JBrowse link
G PITPNM3 PITPNM family member 3 enables ISO (PMID:10022914) UniProt PMID:10022914 NCBI chr16:5,830,107...5,934,979
Ensembl chr16:5,834,088...5,916,697 		JBrowse link
G PLCG1 phospholipase C gamma 1 enables ISO (MGI:3772008|PMID:12367511) UniProt PMID:12367511 MGI:3772008 NCBI chr 2:22,599,547...22,638,394 JBrowse link
G PLCG1 phospholipase C gamma 1 enables IEA Ensembl GO_REF:0000107 Ensembl chr 2:22,604,043...22,637,967 JBrowse link
G PSPN persephin enables IEA InterPro GO_REF:0000002 Ensembl chr 6:5,991,457...5,992,012 JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:13,385,681...13,459,180
Ensembl chr 2:13,387,727...13,459,105 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 enables ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:15115663 GO_REF:0000107 GO_REF:0000118 RGD:1601572 NCBI chr11:107,658,495...107,754,457
Ensembl chr11:107,658,453...107,752,637 		JBrowse link
G PTPN14 protein tyrosine phosphatase non-receptor type 14 enables IEA Ensembl GO_REF:0000107 NCBI chr25:15,023,914...15,228,680
Ensembl chr25:15,110,687...15,219,492 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 enables ISO (PMID:18819921) UniProt PMID:18819921 NCBI chr18:71,302,082...71,400,201
Ensembl chr18:71,310,577...71,345,960 		JBrowse link
G PTPRF protein tyrosine phosphatase receptor type F ISO RGD PMID:16415345 RGD:1642742 NCBI chr20:89,192,426...89,284,989
Ensembl chr20:89,191,660...89,284,970 		JBrowse link
G RACK1 receptor for activated C kinase 1 enables IEA Ensembl GO_REF:0000107 NCBI chr23:82,800,211...82,805,769
Ensembl chr23:82,798,085...82,805,936 		JBrowse link
G RASA1 RAS p21 protein activator 1 ISO RGD PMID:10708762 RGD:1642649 NCBI chr 4:81,249,851...81,371,486
Ensembl chr 4:81,249,805...81,370,453 		JBrowse link
G RASGRF1 Ras protein specific guanine nucleotide releasing factor 1 ISO RGD PMID:10691301 RGD:10003117 NCBI chr26:4,298,091...4,431,606
Ensembl chr26:4,299,116...4,432,420 		JBrowse link
G RNF41 ring finger protein 41 enables ISO (PMID:27353365) CAFA PMID:27353365 NCBI chr11:52,151,968...52,175,760
Ensembl chr11:52,141,715...52,175,728 		JBrowse link
G SHC1 SHC adaptor protein 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr20:8,854,189...8,866,406
Ensembl chr20:8,858,458...8,866,610 		JBrowse link
G SHC3 SHC adaptor protein 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr12:99,503,936...99,672,438
Ensembl chr12:99,506,647...99,669,792 		JBrowse link
G SHC4 SHC adaptor protein 4 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr26:34,319,831...34,467,072
Ensembl chr26:34,329,322...34,467,211 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 enables IEA Ensembl GO_REF:0000107 NCBI chr14:60,330,192...60,335,477
Ensembl chr14:60,431,401...60,433,011
Ensembl chr14:60,431,401...60,433,011 		JBrowse link
G STAP1 signal transducing adaptor family member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:1,330,761...1,380,503
Ensembl chr 7:1,330,223...1,379,820 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 enables ISO (MGI:5306304|PMID:16801538) UniProt
RGD		 PMID:16801538 MGI:5306304 RGD:10043330 NCBI chr 2:60,573,187...61,015,599
Ensembl chr 2:60,865,819...61,017,191 		JBrowse link
G TOB1 transducer of ERBB2, 1 enables IEA Ensembl GO_REF:0000107 NCBI chr16:42,479,823...42,483,964
Ensembl chr16:42,482,161...42,483,198 		JBrowse link
G TP53 tumor protein p53 enables IEA Ensembl GO_REF:0000107 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma ISO RGD PMID:15604144 RGD:2317103 NCBI chr28:10,462,984...10,494,500
Ensembl chr28:10,462,859...10,494,457 		JBrowse link
G ZPR1 ZPR1 zinc finger enables IEA Ensembl GO_REF:0000107 NCBI chr 1:108,144,247...108,153,533
Ensembl chr 1:108,144,609...108,153,480 		JBrowse link
transmembrane receptor protein tyrosine kinase adaptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DOK2 docking protein 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:19,979,303...19,984,022
Ensembl chr 8:19,979,298...19,984,263 		JBrowse link
G FRS2 fibroblast growth factor receptor substrate 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:65,097,789...65,208,373
Ensembl chr11:65,197,385...65,208,379 		JBrowse link
G FRS3 fibroblast growth factor receptor substrate 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr17:30,383,336...30,392,964
Ensembl chr17:30,386,484...30,393,095 		JBrowse link
G GAB2 GRB2 associated binding protein 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:69,422,517...69,624,411
Ensembl chr 1:69,424,100...69,624,279 		JBrowse link
G GRB2 growth factor receptor bound protein 2 enables ISO (PMID:17881575) MGI PMID:17881575 NCBI chr16:46,264,818...46,346,426
Ensembl chr16:46,264,825...46,347,156 		JBrowse link
G IRS1 insulin receptor substrate 1 enables ISO PMID:18285345
(PMID:11784871)
(PMID:12483226), (PMID:8649419)		 BHF-UCL
MGI		 PMID:8649419 PMID:11784871 PMID:12483226 PMID:18285345 RGD:8553881 NCBI chr10:112,748,283...112,812,368 JBrowse link
G IRS2 insulin receptor substrate 2 enables ISO (PMID:7534300) MGI PMID:7534300 NCBI chr 3:88,045,439...88,076,468 JBrowse link
G LOC103223589 GRB2-associated-binding protein 4 enables IEA TreeGrafter GO_REF:0000118 NCBI chr19:1,024,325...1,073,723
Ensembl chr19:1,025,212...1,055,693 		JBrowse link
G SH2B1 SH2B adaptor protein 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 5:26,197,483...26,208,332
Ensembl chr 5:26,196,778...26,207,398 		JBrowse link
G SH2B2 SH2B adaptor protein 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr28:10,862,922...10,900,967
Ensembl chr28:10,864,188...10,883,437 		JBrowse link
G SH2B3 SH2B adaptor protein 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr11:106,657,601...106,703,940
Ensembl chr11:106,670,685...106,700,619 		JBrowse link
G SHC1 SHC adaptor protein 1 enables ISO (PMID:12483226), (PMID:7799946) MGI PMID:7799946 PMID:12483226 NCBI chr20:8,854,189...8,866,406
Ensembl chr20:8,858,458...8,866,610 		JBrowse link
G STAP1 signal transducing adaptor family member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:1,330,761...1,380,503
Ensembl chr 7:1,330,223...1,379,820 		JBrowse link
G TRADD TNFRSF1A associated via death domain enables IEA TreeGrafter GO_REF:0000118 NCBI chr 5:60,296,777...60,303,076
Ensembl chr 5:60,297,375...60,303,579 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18050
    binding 16493
      protein binding 14613
        signaling receptor binding 1507
          receptor tyrosine kinase binding 85
            transmembrane receptor protein tyrosine kinase adaptor activity 14
Path 2
Term Annotations click to browse term
  molecular_function 18050
    binding 16493
      protein binding 14613
        enzyme binding 2307
          kinase binding 883
            protein kinase binding 791
              protein tyrosine kinase binding 135
                receptor tyrosine kinase binding 85
                  transmembrane receptor protein tyrosine kinase adaptor activity 14
paths to the root